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Dick van Soolingen Selected Research

Thioridazine (Mellaril)

1/2016Thioridazine Alters the Cell-Envelope Permeability of Mycobacterium tuberculosis.
12/2014Enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine is not reflected by improved in vivo therapeutic efficacy.
10/2014Enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine is not reflected by improved in vivo therapeutic efficacy.
12/2012The added effect of thioridazine in the treatment of drug-resistant tuberculosis.
2/2012Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine.
9/2010The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis.
6/2010Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!

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Dick van Soolingen Research Topics

Disease

54Tuberculosis (Tuberculoses)
01/2022 - 01/2004
24Infections
04/2022 - 11/2003
14Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)
01/2021 - 05/2010
7Extensively Drug-Resistant Tuberculosis
01/2020 - 06/2010
3Lung Diseases (Lung Disease)
01/2016 - 07/2014
2Coinfection
01/2018 - 01/2013
1Chemical and Drug Induced Liver Injury
12/2018
1Nontuberculous Mycobacterium Infections
10/2016
1Ototoxicity
12/2015
1Lymphadenitis (Adenitis)
10/2011
1Respiratory Tract Infections (Respiratory Tract Infection)
08/2011
1Peripheral Nervous System Diseases (PNS Diseases)
08/2010
1Weight Gain
06/2010
1Pulmonary Tuberculosis
06/2010
1Rheumatic Diseases (Rheumatism)
12/2008
1Meningeal Tuberculosis (Tuberculous Meningitis)
11/2006
1Leg Ulcer
11/2005
1Cicatrix (Scar)
11/2005
1Infection with Mycobacterium marinum
12/2002

Drug/Important Bio-Agent (IBA)

32Pharmaceutical PreparationsIBA
04/2022 - 05/2007
12Rifampin (Rifampicin)FDA LinkGeneric
01/2022 - 08/2007
9Anti-Bacterial Agents (Antibiotics)IBA
01/2017 - 05/2009
8Isoniazid (Ftivazide)FDA LinkGeneric
01/2022 - 08/2007
7DNA (Deoxyribonucleic Acid)IBA
10/2018 - 01/2004
7Thioridazine (Mellaril)FDA LinkGeneric
01/2016 - 06/2010
4VaccinesIBA
01/2020 - 01/2004
3Moxifloxacin (Avelox)FDA Link
01/2022 - 08/2011
3PyrazinamideFDA LinkGeneric
11/2018 - 09/2010
3Clarithromycin (Biaxin)FDA LinkGeneric
01/2017 - 12/2013
3Proteins (Proteins, Gene)FDA Link
01/2017 - 12/2002
3Linezolid (Zyvox)FDA Link
12/2013 - 08/2010
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2009 - 07/2007
2Ethambutol (Myambutol)FDA LinkGeneric
04/2022 - 08/2007
2Levofloxacin (Levaquin)FDA Link
01/2017 - 10/2016
2Ertapenem (Invanz)FDA Link
01/2017 - 04/2016
2Carbapenems (Carbapenem Antibiotics)IBA
01/2017 - 04/2016
2Amikacin (A.M.K)FDA LinkGeneric
10/2016 - 12/2015
2Antipsychotic Agents (Antipsychotics)IBA
01/2016 - 09/2010
2CytokinesIBA
10/2013 - 10/2010
2Antitubercular AgentsIBA
01/2012 - 02/2009
2AntigensIBA
05/2010 - 04/2005
2AntibodiesIBA
12/2008 - 04/2004
2Biological ProductsIBA
12/2008 - 11/2003
1MacrolidesIBA
04/2022
1Interleukin-12 (IL 12)IBA
12/2019
1AcetyltransferasesIBA
12/2018
1Infliximab (Remicade)FDA Link
01/2018
1Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric
01/2017
1Virulence Factors (Pathogenicity Factors)IBA
01/2017
1Cefoxitin (Cefoxitin Sodium)FDA LinkGeneric
10/2016
1Biomarkers (Surrogate Marker)IBA
05/2016
1Tigecycline (Tygacil)FDA Link
01/2016
1Acetylcysteine (Siran)FDA LinkGeneric
11/2013
1Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric
08/2013
11,3- dimethyl- 1,3- bis(4- fluorophenyl)- 1,3- bis(3- (1- (4- butypiperazinyl))propyl)disiloxaneIBA
05/2013
1Indicators and Reagents (Reagents)IBA
01/2013
1SolutionsIBA
06/2012
1FluoroquinolonesIBA
08/2011
1Ciprofloxacin (Cipro)FDA LinkGeneric
08/2011
1LipidsIBA
05/2010
1Tumor Necrosis Factor InhibitorsIBA
12/2008
1InterleukinsIBA
12/2008
1Benzophenoneidum (Auramine O)IBA
07/2008
1A-Form DNA (A-DNA)IBA
07/2008
1lipoarabinomannan (LAM)IBA
04/2008
116S Ribosomal RNAIBA
03/2008
1Streptomycin (Streptomycin Sulfate)FDA Link
08/2007
1Colloids (Colloid)IBA
11/2005
1Listeria monocytogenes hlyA protein (listeriolysin O)IBA
09/2005
1AerosolsIBA
09/2005
1Subunit VaccinesIBA
04/2005
1Explosive Agents (Explosives)IBA
07/2004
1Interferon-gamma (Interferon, gamma)IBA
07/2004
1Tuberculin (PPD)IBA
12/2002

Therapy/Procedure

10Therapeutics
10/2016 - 11/2005
2Drug Therapy (Chemotherapy)
01/2015 - 11/2003
2Duration of Therapy
05/2013 - 08/2011
1Aftercare (After-Treatment)
10/2010
1Oral Administration
09/2010